Akne skarlarının (izlerinin) fraksiyonel lazer fototermoliz ile başarılı bir şekilde tedavi edilebildiğine dair son bilimsel çalışmalardan ikisi. İkisi de prestijli dergilerde yayınlanmış.tedavi ayda bir 3 seans şeklinde uygulanmış ve her seans sonrası belirgin düzelme görülmüş. Yan etki olarak geçici şişilk ve kızarıklık gözlenmiş.
Dermatol Surg. 2007 Mar;33(3):295-9.
The use of fractional laser photothermolysis for the treatment of atrophic scars
Alster TS, Tanzi EL, Lazarus M.
BACKGROUND: Patients with atrophic scars commonly seek treatment for their removal but are often concerned about the prolonged recovery, short-lived results, and/or ineffectiveness of available therapies. A novel treatment using a 1,550-nm erbium-doped fiber laser to induce fractional photothermolysis of treated skin has been used to resurface photodamaged skin but has not been studied previously in patients with atrophic scars to determine its effectiveness for this condition. PURPOSE: To determine the effectiveness and safety of 1,550-nm erbium-doped fiber laser treatment on atrophic scars. METHODS: Fifty-three patients (skin phototypes I-V) with mild to moderate atrophic facial acne scars received monthly treatment with a 1,550-nm erbium-doped fiber laser (Fraxel, Reliant Technologies Inc., San Diego, CA). Clinical response to treatment was determined at each treatment visit and 6 months after the final treatment session by two independent assessors using a quartile grading scale. Side effects and patient satisfaction were monitored at each follow-up visit. RESULTS: Clinical improvement averaged 51% to 75% in nearly 90% of patients after three monthly laser treatments. Mean improvement scores increased proportionately with each successive laser session. Clinical response rates were independent of age, gender, or skin phototype. Side effects included transient erythema and edema in most patients, but no dyspigmentation, ulceration, or scarring. CONCLUSIONS: Atrophic scars can be effectively and safely reduced with 1,550-nm erbium-doped fiber laser treatment.
J Dermatolog Treat. 2008;19(1):45-9
Fractional photothermolysis for the treatment of acne scars: A report of 27 Korean patients
Lee HS, Lee JH, Ahn GY, Lee DH, Shin JW, Kim DH, Chung JH.
Gowoonsesang Dermatology Clinic.
Objectives: Atrophic post-acne scarring remains a therapeutically challenging condition despite various currently available technologies. Fractional photothermolysis (FP) is a novel concept of cutaneous resurfacing which induces non-contiguous microscopic thermal injury. The aim of this study is to evaluate the safety and efficacy of FP in the treatment of acne scars in Asian patients. Methods: A total of 27 Korean patients (Fitzpatrick skin types IV or V) with moderate to severe facial acne scars received three to five sessions of FP treatment (Fraxeltrade mark Laser; Reliant Technologies, CA, USA), each spaced 3-4 weeks apart. Standardized digital photographs were obtained before each treatment and 3 months after the final treatment. In addition, the patients’ perceived degrees of improvement were assessed 3 months after the final treatment using a five-point grading scale. Results: FP led to marked improvement in the appearance of acne scars at 3 months post-treatment. Patients’ self-assessed degrees of improvement were as follows: excellent improvement in eight patients (30%), significant improvement in 16 patients (59%), and moderate improvement in three patients (11%). Adverse events were limited to transient pain, erythema and edema. Conclusions: The 1550-nm erbium-doped FP is associated with significant patient-reported improvement in the appearance of acne scars, with minimal downtime.